๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

GROWTH INHIBITION OF RENAL CANCER CELLS BY HISTONE DEACETYLASE INHIBITORS, SUBEROYLANILIDE HYDROXAMIC ACID (SAHA) AND PXD101

โœ Scribed by Min, Gyeong Eun; Hwang, Jung Jin; Yoo, Changhee; Kim, Mi-Joung; Kim, Yong-Sook; Song, Kanghyon; Kim, Seong Cheol; Kwon, Taek Min; Park, Jong Yeon; Ahn, Tai Young; Kim, Choung-Soo


Book ID
123461525
Publisher
Lippincott Williams and Wilkins
Year
2008
Tongue
English
Weight
122 KB
Volume
179
Category
Article
ISSN
0022-5347

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## Abstract Tumor suppressor genes are often silenced in human cancer; this can occur by transcriptional repression by deacetylation in the promoter regions, mediated by histone deacetylase (HDAC). HDAC inhibitors can block cancer cell growth by restoring expression of tumor suppressor genes. In th