✦ LIBER ✦

Novel Inhibitors of Human Histone Deacetylases: Design, Synthesis, Enzyme Inhibition, and Cancer Cell Growth Inhibition of SAHA-Based Non-hydroxamates

✍ Scribed by Suzuki, Takayoshi; Nagano, Yuki; Kouketsu, Akiyasu; Matsuura, Azusa; Maruyama, Sakiko; Kurotaki, Mineko; Nakagawa, Hidehiko; Miyata, Naoki

Book ID: 123609223
Publisher: American Chemical Society
Year: 2005
Tongue: English
Weight: 319 KB
Volume: 48
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm049207j

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Novel Histone Deacetylase Inhibitors: De

Novel Histone Deacetylase Inhibitors: Design, Synthesis, Enzyme Inhibition, and Binding Mode Study of SAHA-Based Non-Hydroxamates.

✍ Takayoshi Suzuki; Yuki Nagano; Azusa Matsuura; Arihiro Kohara; Shin-ichi Ninomiy 📂 Article 📅 2004 🏛 John Wiley and Sons ⚖ 75 KB 👁 1 views

Histone deacetylase inhibitor, suberoyla

Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (Vorinostat, SAHA) profoundly inhibits the growth of human pancreatic cancer cells

✍ Takashi Kumagai; Naoki Wakimoto; Dong Yin; Sigal Gery; Norihiko Kawamata; Noriyu 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 French ⚖ 461 KB 👁 1 views

## Abstract Tumor suppressor genes are often silenced in human cancer; this can occur by transcriptional repression by deacetylation in the promoter regions, mediated by histone deacetylase (HDAC). HDAC inhibitors can block cancer cell growth by restoring expression of tumor suppressor genes. In th

GROWTH INHIBITION OF RENAL CANCER CELLS

GROWTH INHIBITION OF RENAL CANCER CELLS BY HISTONE DEACETYLASE INHIBITORS, SUBEROYLANILIDE HYDROXAMIC ACID (SAHA) AND PXD101

✍ Min, Gyeong Eun; Hwang, Jung Jin; Yoo, Changhee; Kim, Mi-Joung; Kim, Yong-Sook; 📂 Article 📅 2008 🏛 Lippincott Williams and Wilkins 🌐 English ⚖ 122 KB

Synthesis, Enzymatic Inhibition, and Can

Synthesis, Enzymatic Inhibition, and Cancer Cell Growth Inhibition of Novel δ-Lactam-Based Histone Deacetylase (HDAC) Inhibitors.

✍ Gyoonhee Han; et al. et al. 📂 Article 📅 2006 🏛 John Wiley and Sons ⚖ 18 KB 👁 1 views

Synthesis, enzymatic inhibition, and can

Synthesis, enzymatic inhibition, and cancer cell growth inhibition of novel δ-lactam-based histone deacetylase (HDAC) inhibitors

✍ Hwan Mook Kim; Kiho Lee; Bum Woo Park; Dong Kyu Ryu; Kangjeon Kim; Chang Woo Lee 📂 Article 📅 2006 🏛 Elsevier Science 🌐 English ⚖ 112 KB

Design, Synthesis, Structure−Selectivity

Design, Synthesis, Structure−Selectivity Relationship, and Effect on Human Cancer Cells of a Novel Series of Histone Deacetylase 6-Selective Inhibitors

✍ Itoh, Yukihiro; Suzuki, Takayoshi; Kouketsu, Akiyasu; Suzuki, Nobuaki; Maeda, Sa 📂 Article 📅 2007 🏛 American Chemical Society 🌐 English ⚖ 500 KB