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Glutamate-mediated overexpression of CD38 in astrocytes cultured with neurones

✍ Scribed by Santina Bruzzone; Claudia Verderio; Ursula Schenk; Ernesto Fedele; Elena Zocchi; Michela Matteoli; Antonio De Flora

Book ID
111178147
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
172 KB
Volume
89
Category
Article
ISSN
0022-3042

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## Abstract Generation of reactive oxygen species (ROS) in brain tissue leads to neurodegeneration. The major source of ROS is the mitochondrial respiratory chain. We studied regulation of Ca^2+^ level, mitochondrial potential, and ROS generation in defined mixed hippocampal cell cultures exposed t