The extracellular glutamate concentration is kept low by glutamate transporters in the plasma membranes. Here we have studied the expression of the glutamate transporters GLAST, GLT and EAAC during the in vitro development of embryonic hippocampal neurons grown in a defined (serum free) medium. Immu
✦ LIBER ✦
Astrocytes repress the neuronal expression of GLAST and GLT glutamate transporters in cultured hippocampal neurons from embryonic rats
✍ Scribed by Céline Plachez; Alexandra Martin; Janique Guiramand; Max Récasens
- Book ID
- 116764547
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 589 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0197-0186
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## Abstract Sublethal ischemia leads to increased tolerance against subsequent prolonged cerebral ischemia in vivo. In the present study, we investigated the roles of the astrocytic glutamate (Glu) transporter GLT‐1 in preconditioning (PC)‐induced neuronal ischemic tolerance in cortical neuron/astr