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Glial cell-derived neurotrophic factor upregulates the expression and activation of matrix metalloproteinase-9 in human pancreatic cancer

✍ Scribed by Yuji Okada; Guido Eibl; John P. Duffy; Howard A. Reber; Oscar J. Hines

Book ID
119767464
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
692 KB
Volume
134
Category
Article
ISSN
0039-6060

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Glial cell line-derived neurotrophic factor (GDNF) has been shown to exert neurotrophic effects on motor neurons as well as mesencephalic dopaminergic neurons. Because GDNF promotes survival of motor neurons in vivo and in vitro and rescues motor neurons from naturally occurring cell death, the pote