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Expression of glial cell line-derived neurotrophic factor (GDNF) in the developing human fetal brain

✍ Scribed by H. Koo; B.H. Choi

Book ID
117563532
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
906 KB
Volume
19
Category
Article
ISSN
0736-5748

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Human SK-N-AS neuroblastoma and U-87MG glioblastoma cell lines were found to secrete relatively high levels of glial cell line-derived neurotrophic factor (GDNF). In response to growth factors, cytokines, and pharmacophores, the two cell lines differentially regulated GDNF release. A 24-hr exposure