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Germline CDKN2A/p16 mutations are rare in multiple primary and familial malignant melanoma in German patients

✍ Scribed by Lukowsky, Ansgar; Schäfer-Hesterberg, Gregor; Sterry, Wolfram; Voit, Christiane

Book ID
119293311
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
262 KB
Volume
49
Category
Article
ISSN
0923-1811

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## Abstract Germline mutations in the __CDKN2A__ gene have been shown to predispose individuals to cutaneous malignant melanoma. Here, we describe three melanoma‐prone families and one isolated patient affected by multiple melanoma who carried a tandem germline mutation of __CDKN2A__ at the nucleot