𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Two p16 (CDKN2A) germline mutations in 30 Israeli melanoma families

✍ Scribed by Yakobson, Emanuel; Shemesh, Pnina; Azizi, Esther; Winkler, Eyal; Lassam, Norman; Hogg, David; Brookes, Sharon; Peters, Gordon; Lotem, Michal; Zlotogorski, Abraham


Book ID
110024998
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
256 KB
Volume
8
Category
Article
ISSN
1018-4813

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Germline p16 mutations in familial melan
✍ Hussussian, Christopher J.; Struewing, Jeffery P.; Goldstein, Alisa M.; Higgins, πŸ“‚ Article πŸ“… 1994 πŸ› Nature Publishing Group 🌐 English βš– 683 KB
Familial melanoma, pancreatic cancer and
✍ Alisa M. Goldstein πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 78 KB πŸ‘ 1 views

Germline CDKN2A mutations have been observed in approximately 20 percent of familial melanoma kindreds from North America, Europe and Australasia. There is also an increased risk of pancreatic cancer in a subset of families with mutations, however, the precise relationship between the CDKN2A gene an

CDKN2A mutations in melanoma families fr
✍ A.L. Borges; F. CuΓ©llar; J.A. Puig-ButillΓ©; M. Scarone; L. Delgado; C. Badenas; πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 149 KB
CDKN2A (p16INK4A) somatic and germline m
✍ Birgitte Smith-SΓΈrensen; Eivind Hovig πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 836 KB

The cell cycle is composed of a series of steps that can be negatively or positively regulated by various factors. A group of low-molecular-weight proteins have recently been identified that specifically inhibit the function of cyclin-dependent kinases in mammalian cells. Inactivation of the CDKNZA