𝔖 Bobbio Scriptorium
✦   LIBER   ✦

CDKN2A and MC1R Mutations in Patients with Sporadic Multiple Primary Melanoma

✍ Scribed by Peris, Ketty; Fargnoli, Maria Concetta; Pacifico, Alessia; Surrenti, Tiziana; Stolz, Wilhem; Wolf, Peter; Soyer, Hans Peter; Chimenti, Sergio

Book ID
110733169
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
294 KB
Volume
122
Category
Article
ISSN
0022-202X

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Sporadic multiple primary melanoma cases
Sporadic multiple primary melanoma cases: CDKN2A germline mutations with a founder effect
✍ Stéphane Auroy; Marie-Françoise Avril; Agnès Chompret; Danièle Pham; Alisa M. Go 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 122 KB

## Abstract Multiple primary cancers are one of the hallmarks of inherited predisposition. Outside the familial context, multiple primary tumors could be related either to germline de novo mutations or to low‐penetrance mutations, in predisposing genes. We selected 100 patients who displayed multip

Population-based prevalence of CDKN2A an
Population-based prevalence of CDKN2A and CDK4 mutations in patients with multiple primary melanomas
✍ Per Helsing; Dag Andre Nymoen; Sarah Ariansen; Solrun J. Steine; Lovise Maehle; 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 256 KB 👁 1 views

## Abstract The presence of multiple primary cutaneous melanomas (MPM) has been advocated as guidance to identifying melanoma families. Frequencies of __CDKN2A__ mutations in materials of sporadic MPM cases from pigmented lesion clinics vary between 8 and 15%. Patients with MPM have therefore been

New founder germline mutations of CDKN2A
New founder germline mutations of CDKN2A in melanoma-prone families and multiple primary melanoma development in a patient receiving levodopa treatment
✍ Caroline Kannengiesser; Stéphane Dalle; Marie-Thérèse Leccia; Marie Françoise Av 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 372 KB 👁 1 views

## Abstract Germline mutations in the __CDKN2A__ gene have been shown to predispose individuals to cutaneous malignant melanoma. Here, we describe three melanoma‐prone families and one isolated patient affected by multiple melanoma who carried a tandem germline mutation of __CDKN2A__ at the nucleot