## Background Uterine serpins are members of the serine proteinase inhibitor superfamily. Like some other serpins, these proteins do not appear to be functional proteinase inhibitors. The most studied member of the group, ovine uterine serpin (OvUS), inhibits proliferation of several cell types inc
Geranylgeranylpyrophosphate, a Metabolite of Mevalonate, Regulates the Cell Cycle Progression and DNA Synthesis in Human Lymphocytes
β Scribed by Ichiro Tatsuno; Tomoaki Tanaka; Tooru Oeda; Tatsuji Yasuda; Masatoshi Kitagawa; Yasushi Saito; Aizan Hirai
- Book ID
- 115581328
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 306 KB
- Volume
- 241
- Category
- Article
- ISSN
- 0006-291X
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There are few data available on cell cycle events that occur when proliferation of normal cells in culture is curtailed due to "natural aging" of the culture conditions. Stathmokinetic and cytofluorometry studies were performed on PHA-stimulated human lymphocyte cultures for eight consecutive days.
## Abstract Acetophthalidin [(Β±)β3βacetylβ5,7βdihydroxyphthalide (1)] was synthesized from 6,8βdiacetoxyβ3βmethylisocoumarin (8) by its epoxidation followed by hydrolysis.