Synthetic Microbial Chemistry, XXX. Synthesis of Acetophthalidin, a Fungal Metabolite which Inhibits the Progression of the Mammalian Cell Cycle

✍ Scribed by Nomoto, Shin ;Mori, Kenji

• Publisher: John Wiley and Sons
• Year: 1997
• Tongue: English
• Weight: 330 KB
• Volume: 1997
• Category: Article
• ISSN: 0947-3440
• DOI: 10.1002/jlac.199719970412

✦ Synopsis

Abstract

Acetophthalidin [(±)‐3‐acetyl‐5,7‐dihydroxyphthalide (1)] was synthesized from 6,8‐diacetoxy‐3‐methylisocoumarin (8) by its epoxidation followed by hydrolysis.