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Targeted neutralization of calmodulin in the nucleus blocks DNA synthesis and cell cycle progression

✍ Scribed by Jiahong Wang; Katheryn M. Moreira; Begoña Campos; Marcia A. Kaetzel; John R. Dedman

Book ID: 116106472
Publisher: Elsevier Science
Year: 1996
Tongue: English
Weight: 421 KB
Volume: 1313
Category: Article
ISSN: 0167-4889
DOI: 10.1016/0167-4889(96)00093-6

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## Abstract The relationship between DNA synthesis and protein accumulation in cell nucleus and cytoplasm has been investigated by the use of a combination of ultramicrointerferometric and ultramicrospectrophotometric methods. 5‐Fluoro‐2'‐deoxyuridine (FUdR) inhibited DNA synthesis, resulting in i