𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Genomic rearrangements of the c-myc proto-oncogene in human malignant lymphomas

✍ Scribed by Dr A. S. Jack; Susan J. Gardner; K. I. Mills; M. H. Goyns; F. D. Lee; G. D. Birnie


Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
667 KB
Volume
149
Category
Article
ISSN
0022-3417

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Somatic rearrangement of the c-myc oncog
✍ Georgia Chenevix-Trench; Frederick G. Behm; Eric H. Westin πŸ“‚ Article πŸ“… 1986 πŸ› John Wiley and Sons 🌐 French βš– 943 KB

Chromosome translocations involving 8q24, the band to which c-myc has been mapped (Dalla-Favera et a/., 1982). are a uniform finding in Burkitt's lymphoma (Bernheim et a/., 1981). However, in only a minority of the tumors is the rearrangement of the cmyc locus sufficiently close to the gene to be de

Amplification of the c-myc proto-oncogen
✍ Dr. Vicki V. Baker; Kenneth D. Hatch; Hugh M. Shingleton πŸ“‚ Article πŸ“… 1988 πŸ› John Wiley and Sons 🌐 English βš– 357 KB

Amplification without structural rearrangements of the c-myc proto-oncogene was found in 14 of 44 primary cervical neoplasms. There was no apparent correlation with stage of disease or degree of cellular differentiation. The prognostic significance of c-myc amplification cannot be determined from th

Genomic organization and expression of t
✍ Demetrios Kalaitzidis; Thomas D. Gilmore πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 258 KB

## Abstract The human large B‐cell lymphoma cell line RC‐K8 has a rearranged __REL__ locus that is transcribed into a chimeric mRNA, termed __REL‐NRG__ (__N__on‐__R__el __G__ene). By analyzing the recently completed human genome sequence, we have found that the normal __REL__ and __NRG__ loci are s

Differential expression of c-erbB, c-myc
✍ Pradip Roy-Burman; B. Gayathri Devi; John W. Parker πŸ“‚ Article πŸ“… 1983 πŸ› John Wiley and Sons 🌐 French βš– 688 KB

## Abstract Total cellular polyadenylated RNA from a variety of fresh human lymphoma and leukemia cells, characterized by histopathology and certain cell surface markers, was analyzed for the expression of three distinct cellular oncogenes (__c‐oncgenes__), __c‐erbB, c‐myc__ and __c‐myb__ by dotblo

Amplification of c-myc and c-erbB-2 prot
✍ M. Gutman; Y. Ravia; D. Assaf; T. Yamamoto; R. Rozin; Y. Shiloh πŸ“‚ Article πŸ“… 1989 πŸ› John Wiley and Sons 🌐 French βš– 604 KB

Molecular probes for cellular proto-oncogenes have recently been extensively used in order to search for functional and structural alterations in tumor tissues. Variable, and sometimes contradictory, results have been obtained regarding the frequency and clinical significance of amplification of the