✦ LIBER ✦

Amplification of the c-myc proto-oncogene in cervical carcinoma

✍ Scribed by Dr. Vicki V. Baker; Kenneth D. Hatch; Hugh M. Shingleton

Publisher: John Wiley and Sons
Year: 1988
Tongue: English
Weight: 357 KB
Volume: 39
Category: Article
ISSN: 0022-4790
DOI: 10.1002/jso.2930390403

No coin nor oath required. For personal study only.

✦ Synopsis

Amplification without structural rearrangements of the c-myc proto-oncogene was found in 14 of 44 primary cervical neoplasms. There was no apparent correlation with stage of disease or degree of cellular differentiation. The prognostic significance of c-myc amplification cannot be determined from this study.

📜 SIMILAR VOLUMES

Dynamic regulation of c-Myc proto-oncoge

Dynamic regulation of c-Myc proto-oncogene expression during lymphocyte development revealed by a GFP-c-Myc knock-in mouse

✍ Ching-Yu Huang; Andrea L. Bredemeyer; Laura M. Walker; Craig H. Bassing; Barry P 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 384 KB

Amplification and expression of the c-er

Amplification and expression of the c-erb B-2/neu proto-oncogene in human bladder cancer

✍ Haiyen E. Zhau; Xin Zhang; Andrew C. Von Eschenbach; Kathleen Scorsone; R. Josep 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 466 KB

## Abstract The c‐__erb__ B‐2/__neu__ gene encodes a cell‐surface glycoprotein with extensive homology to, but distinct from, the epidermal growth‐factor receptor. In this study, we compared the c‐__erb__ B‐2/__neu__ gene amplification and expression of tissue specimens obtained from the bladders o

Over-expression and amplification of the

Over-expression and amplification of the c-myc gene in human urothelial carcinoma

✍ Frank Christoph; Bettina Schmidt; Bernd J. Schmitz-Dräger; Wolfgang A. Schulz 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 French ⚖ 65 KB 👁 2 views

To understand the mechanisms underlying increased expression of Myc protein in human urinary bladder cancer, expression of c-myc mRNA and the copy number of the c-myc gene were determined. Expression of mRNA was measured by quantitative RT-PCR in 40 urothelial carcinomas and in 18 histologically nor

Expression of hepatocyte growth factor a

Expression of hepatocyte growth factor and its receptor, the c-met proto-oncogene, in hepatocellular carcinoma

✍ T Ueki; J Fujimoto; T Suzuki; H Yamamoto; E Okamoto 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 237 KB

mal and malignant epithelial cells and several other cell The c-met proto-oncogene encodes the tyrosine kinase types, including endothelial cells and melanocytes. 4,5 receptor for hepatocyte growth factor (HGF), a potent It has been reported that the expression of c-Met is enmitogen and motogen for

Expression of hepatocyte growth factor a

Expression of hepatocyte growth factor and its receptor c-met proto-oncogene in hepatocellular carcinoma

✍ T Ueki; J Fujimoto; T Suzuki; H Yamamoto; E Okamoto 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 240 KB

The c-met proto-oncogene encodes the tyrosine kinase receptor for hepatocyte growth factor (HGF), a potent mitogen and motogen for epithelial cells. Because of its profound effects on cell growth and motility, HGF may be important in the development of cancer metastases in hepatocellular carcinoma (

Expression of cellular oncogenes in huma

Expression of cellular oncogenes in human gastric carcinoma: c-myc, c–erb B2′ and c-Ha-ras

✍ Dr. Young-Jin Kim; Hoi–dong Ghu; Dong-Yi Kim; Hyun-Jong Kim; Shin-Kon Kim; Chang 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 333 KB

Expression of oncogenes in gastric cancer tissue was evaluated with immunohistochemical staining methods using monoclonal antibodies to products of the oncogenes. Rates of expression in gastric cancer tissue were 50% for c-myc, 72% for c-erb B,, and 56% for c-Ha-rus oncogenes. Expression of these on