Genomic and functional analyses of MUTYH in Japanese patients with adenomatous polyposis
β Scribed by R Yanaru-Fujisawa; T Matsumoto; Y Ushijima; M Esaki; M Hirahashi; M Gushima; T Yao; Y Nakabeppu; M Iida
- Book ID
- 110888599
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 340 KB
- Volume
- 73
- Category
- Article
- ISSN
- 0009-9163
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Pouch function after proctocolectomy and ileal J pouch-anal anastomosis was assessed at 1 and 5 years in 41 patients with familial adenomatous polyposis. The mean(s.d.) stool frequency per 24 h decreased from 4Β·4(1Β·7) to 3Β·9(1Β·8) (P < 0Β·05), the mean(s.d.) nocturnal stool frequency fell
Patients with Familial Adenomatous Polyposis (FAP) manifest numerous colorectal adenomas as well as benign and malignant extra-colonic lesions. Adenomatous polyposis coli (APC) gene mutations are the underlying genetic defect in FAP. We analyzed germline D N A of 81 unrelated FAP patients and evalua
## Development of one hundred or more adenomas in the colon and rectum is diagnostic for the dominantly inherited, autosomal disease Familial Adenomatous Polyposis (FAP). It is possible to identify a mutation in the Adenomatous Polyposis Coli (APC) gene in approximately 80% of the patients, and alm