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Function of ileal J pouch-anal anastomosis in patients with familial adenomatous polyposis

✍ Scribed by C. Penna; E. Tiret; A. Kartheuser; L. Hannoun; B. Nordlinger; Professor R. Parc


Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
337 KB
Volume
80
Category
Article
ISSN
0007-1323

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✦ Synopsis


Abstract

Pouch function after proctocolectomy and ileal J pouch-anal anastomosis was assessed at 1 and 5 years in 41 patients with familial adenomatous polyposis. The mean(s.d.) stool frequency per 24 h decreased from 4Β·4(1Β·7) to 3Β·9(1Β·8) (P < 0Β·05), the mean(s.d.) nocturnal stool frequency fell from 0Β·6(1Β·0) to 0Β·3(0Β·6) (P < 0Β·05), and the number of patients having nocturnal bowel movements decreased from 16 to seven (P < 0Β·05). At 5 years, only one patient still followed a strict diet (versus ten at 1 year, P < 0Β·05) and only two needed antidiarrhoeal medication (versus ten at 1 year, P < 0Β·05). There were no episodes of pouchitis or late reservoir-related complications. The function of ileal pouch-anal anastomosis improves over time in patients with familial adenomatous polyposis.


πŸ“œ SIMILAR VOLUMES


Pouch adenomas in patients with familial
✍ K. P. Nugent; A. D. Spigelman; R. J. Nicholls; I. C. Talbot; K. Neale; Mr R. K. πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 111 KB πŸ‘ 2 views

Familial adenomatous polyposis (FAP) represents a human model of the adenomasarcinoma sequence. Colectomy substantially reduces the cancer risk. Restorative proctocolectomy maintains continence and abolishes the risk of rectal cancer, but there is a price to pay in terms of an increased morbidity ra