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Pouch adenomas in patients with familial adenomatous polyposis

โœ Scribed by K. P. Nugent; A. D. Spigelman; R. J. Nicholls; I. C. Talbot; K. Neale; Mr R. K. S. Phillips

Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
111 KB
Volume
80
Category
Article
ISSN
0007-1323

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โœฆ Synopsis

Familial adenomatous polyposis (FAP) represents a human model of the adenomasarcinoma sequence. Colectomy substantially reduces the cancer risk. Restorative proctocolectomy maintains continence and abolishes the risk of rectal cancer, but there is a price to pay in terms of an increased morbidity rate'. Long suture lines are prone to carcinogenesis experimentally, which raises concern that pouches might themselves be at risk'.

To investigate this hypothesis, this study compared the incidence of ileal pouch adenoma with that of terminal ileal adenoma detected histologically after primary colonic surgery.

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Function of ileal J pouch-anal anastomos
Function of ileal J pouch-anal anastomosis in patients with familial adenomatous polyposis
โœ C. Penna; E. Tiret; A. Kartheuser; L. Hannoun; B. Nordlinger; Professor R. Parc ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 337 KB ๐Ÿ‘ 1 views

## Abstract Pouch function after proctocolectomy and ileal J pouch-anal anastomosis was assessed at 1 and 5 years in 41 patients with familial adenomatous polyposis. The mean(s.d.) stool frequency per 24 h decreased from 4ยท4(1ยท7) to 3ยท9(1ยท8) (P < 0ยท05), the mean(s.d.) nocturnal stool frequency fell