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Genetic variants in carcinogen-metabolizing enzymes, cigarette smoking and pancreatic cancer risk

✍ Scribed by Jang, J.-H.; Cotterchio, M.; Borgida, A.; Gallinger, S.; Cleary, S. P.

Book ID
119971498
Publisher
Oxford University Press
Year
2012
Tongue
English
Weight
122 KB
Volume
33
Category
Article
ISSN
0143-3334

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## Abstract The metabolism of xenobiotics is complex and involves multiple steps and multiple enzymes. Genetic variation in the genes encoding these enzymes as well as the level of exposure to the substrates of these enzymes could alter metabolism and clearance of potential carcinogens and thus alt