Association of genotypes of carcinogen-a
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Shogo Ozawa; Takahiko Katoh; Hisato Inatomi; Hirohisa Imai; Yoshiki Kuroda; Masa
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Article
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2002
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John Wiley and Sons
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French
⚖ 203 KB
Carcinogenic aromatic amines such as 4-aminobiphenyl, which is contained in tobacco smoke, are one of the causal factors of urothelial epithelial cancers. 4-Aminobiphenyl has been shown to be bioactivated through N-hydroxylation by hepatic cytochrome (CYP) 1A2 and subsequently through O-sulfation an