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Combined Effect of Smoking and Polymorphisms in Tobacco Carcinogen-Metabolizing Enzymes CYP1A1 and GSTM1 on the Head and Neck Cancer Risk in North Indians

✍ Scribed by Sharma, Rajni; Ahuja, Monica; Panda, Naresh K; Khullar, Madhu

Book ID
125513421
Publisher
Mary Ann Liebert
Year
2010
Tongue
English
Weight
109 KB
Volume
29
Category
Article
ISSN
1044-5498

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✍ Martin Lacko; Hennie M. J. Roelofs; Rene H. M. te Morsche; Adri C. Voogd; Michae πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 99 KB

## Abstract ## __Background.__ UGT1A7 is an enzyme involved in the metabolism of (pre)carcinogens present in tobacco smoke. We investigated whether genetic polymorphisms in __UGT1A7__, with predicted altered enzyme activity, may have a risk‐modifying effect on head and neck carcinogenesis. ## __M