Genetic variants of folate metabolizing enzymes and epigenetic regulation genes and sporadic colorectal cancer risk
✍ Scribed by S. de Vogel; K.A.D. Wouters; R. Gottschalk; F.J. van Schooten; A.F.P.M. de Goeij; A.P. de Bruïne; R.A. Goldbohm; P.A. van den Brandt; M.P. Weijenberg; M. van Engeland
- Book ID
- 119599116
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 85 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1359-6349
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## Abstract Genetic instability plays a crucial role in cancer development. The genetic stability of the cell as well as DNA methylation status could be modulated by folate levels. Several studies suggested associations between polymorphisms in folate genes and alterations in protein expression and
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