Genetic studies of erythromycin resistant mutants of Escherichia coli
β Scribed by Pardo, D. ;Rosset, R.
- Publisher
- Springer
- Year
- 1974
- Tongue
- English
- Weight
- 602 KB
- Volume
- 135
- Category
- Article
- ISSN
- 0026-8925
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We have studied the in vitro properties of ribosomes from several mutants resistant to erythromycin. Mutations in three different genes may confer resistance to erythromycin. Two of them are structural genes for proteins L4 and L22 of the large subunit. The third mutation (in eryC gene) seems to aff
## Abstract The apramycinβresistant mutants of __E. coli__ were isolated spontaneously. Mutations, __aprA__ and __aprB__, conferring resistance to apramycin were located at 72 min on the __E. coli__ genetic map where most of ribosomal genes were mapped. One of the mutants, carrying the __aprB__ mut
When arsenate-resistant mutants are selected approximately 50 per cent of them are also consitutive for the synthesis of alkaline phosphatase and the Pi-binding protein. Some of these mutants are linked to ilv (phoS- or phoT-), other are linked to proC (phoR-). One of the mutant strains linked to il