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Arsenate-resistant alkaline phosphatase-constitutive mutants of Escherichia coli

✍ Scribed by Yagil, Ezra ;Be'eri, Hagit

Publisher
Springer
Year
1977
Tongue
English
Weight
480 KB
Volume
154
Category
Article
ISSN
0026-8925

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✦ Synopsis

When arsenate-resistant mutants are selected approximately 50 per cent of them are also consitutive for the synthesis of alkaline phosphatase and the Pi-binding protein. Some of these mutants are linked to ilv (phoS- or phoT-), other are linked to proC (phoR-). One of the mutant strains linked to ilv lost the Pi-binding protein (the phoS gene product). Resistance to arsenate, constitutivty for alkaline phosphatase synthesis and loss of the Pi-binding protein occurred pleiotropically by the same phoS- mutation.

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