𝔖 Bobbio Scriptorium
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Genetic linkage: interpreting lod scores

✍ Scribed by Risch, N

Book ID
126235660
Publisher
American Association for the Advancement of Science
Year
1992
Tongue
English
Weight
536 KB
Volume
255
Category
Article
ISSN
0036-8075

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πŸ“œ SIMILAR VOLUMES

Efficiency of lod scores for representin
Efficiency of lod scores for representing multiple locus linkage data
✍ Dr. C. J. Maclean; N. E. Morton; R. Lew; D. C. Rao πŸ“‚ Article πŸ“… 1985 πŸ› John Wiley and Sons 🌐 English βš– 533 KB

The problem of compact, fully efficient representation of multilocus data has not yet been solved. Lod scores can be used to map multilocus data, but because of certain statistical problems, this method loses some information. However, simulation studies show that for distances less than 10 or 20 cM

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Lods, wrods, and mods: The interpretation of lod scores calculated under different models
✍ Dr. Susan E. Hodge; Robert C. Elston πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 884 KB

In this paper we examine the relationships among classical lod scores, "wrod" scores (lod scores calculated under the wrong genetic model), and "mod" scores (lod scores maximized over genetic model parameters). We compare the behavior of these scores when the state of nature is linkage to their beha

Interpretation of LOD scores with a set
Interpretation of LOD scores with a set of marker loci
✍ E. A. Thompson; Walter E. Nance πŸ“‚ Article πŸ“… 1984 πŸ› John Wiley and Sons 🌐 English βš– 315 KB

The problem discussed is that of interpreting LOD scores when multiple markers are tested for linkage with a particular disease locus. Provided the tests are based on independent segregations, both the maximum and the average LOD can be translated into a score that would have the same significance l