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Direct Power Comparisons between Simple LOD Scores and NPL Scores for Linkage Analysis in Complex Diseases

✍ Scribed by Paula C. Abreu; David A. Greenberg; Susan E. Hodge

Book ID: 117852963
Publisher: American Society of Human Genetics
Year: 1999
Tongue: English
Weight: 775 KB
Volume: 65
Category: Article
ISSN: 0002-9297
DOI: 10.1086/302536

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📜 SIMILAR VOLUMES

The Power to Detect Linkage in Complex D

The Power to Detect Linkage in Complex Disease by Means of Simple LOD-Score Analyses

✍ David A. Greenberg; Paula Abreu; Susan E. Hodge 📂 Article 📅 1998 🏛 American Society of Human Genetics 🌐 English ⚖ 593 KB

Estimation and test for linkage between

Estimation and test for linkage between markers: a comparison of lod score andχ2test in a linkage study of maritime pine (Pinus pinasterAit.)

✍ S. Gerber; F. Rodolphe 📂 Article 📅 1994 🏛 Springer 🌐 English ⚖ 409 KB

The first step in the construction of a linkage map involves the estimation and test for linkage between all possible pairs of markers. The lod score method is used in many linkage studies for the latter purpose. In contrast with classical statistical tests, this method does not rely on the choice o