✦ LIBER ✦

Interpretation of LOD scores with a set of marker loci

✍ Scribed by E. A. Thompson; Walter E. Nance

Book ID: 102223587
Publisher: John Wiley and Sons
Year: 1984
Tongue: English
Weight: 315 KB
Volume: 1
Category: Article
ISSN: 0741-0395
DOI: 10.1002/gepi.1370010407

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✦ Synopsis

The problem discussed is that of interpreting LOD scores when multiple markers are tested for linkage with a particular disease locus. Provided the tests are based on independent segregations, both the maximum and the average LOD can be translated into a score that would have the same significance level were it the result of a single test.

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