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Genetic analysis of human salivary α-amylase isozymes by isoelectric focusing

✍ Scribed by P. D. Eckersall; Josie A. Beeley

Publisher
Springer
Year
1981
Tongue
English
Weight
391 KB
Volume
19
Category
Article
ISSN
0006-2928

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✦ Synopsis

The isozymes of human salivary a-amylase have been separated by thinlayer gel isoelectric focusing in a pH 4-8 gradient followed by a starchiodine zymogram procedure. The normal isozyme pattern (N) consisted of five major isozymes together with a number of minor ones. In addition, seven variant isozyme phenotypes were also observed, which had a combined frequency of 11.7% in a random population of 368 individuals. Analysis of familial data is indicative of the inheritance of autosomal codominant alleles.

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