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Gene amplification in pesticide-resistant insects

✍ Scribed by O. Hyrien; G. Buttin

Book ID: 113288438
Publisher: Elsevier Science
Year: 1986
Tongue: English
Weight: 361 KB
Volume: 2
Category: Article
ISSN: 0168-9525
DOI: 10.1016/0168-9525(86)90267-2

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## Multidrug resistance (MDR) is developed in a population of somatic mammalian cells in vivo or in vitro when they are selected for resistance to each of a large group of drugs (colchicine, adriamycin, actinomycin D , etc.). It isproduced by the amplification of some unknown gene@) whose praduct(s)