GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons
β Scribed by Lin, L.; Doherty, D.; Lile, J.; Bektesh, S; Collins, F
- Book ID
- 121445444
- Publisher
- American Association for the Advancement of Science
- Year
- 1993
- Tongue
- English
- Weight
- 982 KB
- Volume
- 260
- Category
- Article
- ISSN
- 0036-8075
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Glial cell line-derived neurotrophic factor (GDNF) was first discovered as a potent survival factor for midbrain dopaminergic neurons and was then shown to rescue these neurons in animal models of Parkinson's disease. GDNF is a more potent survival factor for dopaminergic neurons and the noradrenerg
We compared the effects of glial cell 3 did not promote any detectable level of neuronal line-derived neurotrophic factor (GDNF) on dorsal survival despite the fact that they underwent retroroot ganglion (DRG) sensory neurons to that of nerve growth factor (NGF), brain-derived neurotrophic grade tra