Functions of the poly(ADP-ribose) polymerase superfamily in plants
β Scribed by Rebecca S. Lamb; Matteo Citarelli; Sachin Teotia
- Publisher
- Springer
- Year
- 2011
- Tongue
- English
- Weight
- 655 KB
- Volume
- 69
- Category
- Article
- ISSN
- 1420-682X
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lose affinity chromatography. This part of the purifiand Guy G. Poirier\* ,2 cation was performed according to Yoshihara et al. (7) \*Poly(ADP-ribose) Metabolism Group, Health and as modified in Shah et al. (8). Briefly, the calf thymus
## Abstract Amyloid peptide is thought to play a critical role in neuronal death in Alzheimer's disease (AD), most likely through oxidative stress. Free radicalβrelated injury leads to DNA breaks, which subsequently activates the repair enzyme poly(ADPβribose) polymeraseβ1 (PARPβ1). In this study,