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Functional Characterization of Mammalian Inositol 1,4,5-Trisphosphate Receptor Isoforms

✍ Scribed by Tu, Huiping; Wang, Zhengnan; Nosyreva, Elena; De Smedt, Humbert; Bezprozvanny, Ilya


Book ID
119918975
Publisher
Biophysical Society
Year
2005
Tongue
English
Weight
379 KB
Volume
88
Category
Article
ISSN
0006-3495

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Expression of inositol 1,4,5-trisphospha
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Ca 2Ψ‰ signals mediate the hepatic effects of numerous hormones and growth factors. Hepatic Ca 2Ψ‰ signals are elicited by the inositol trisphosphate receptor, an intracellular Ca 2Ψ‰ channel. Three isoforms of this receptor have been identified; they are expressed and regulated differently. We investi