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Inositol 1,4,5-trisphosphate receptor isoforms show similar Ca2+release kinetics

✍ Scribed by J.L. Dyer; F. Michelangeli


Book ID
114483310
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
197 KB
Volume
30
Category
Article
ISSN
0143-4160

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Expression of inositol 1,4,5-trisphospha
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Ca 2Ψ‰ signals mediate the hepatic effects of numerous hormones and growth factors. Hepatic Ca 2Ψ‰ signals are elicited by the inositol trisphosphate receptor, an intracellular Ca 2Ψ‰ channel. Three isoforms of this receptor have been identified; they are expressed and regulated differently. We investi