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Isoform-Specific Function of Single Inositol 1,4,5-Trisphosphate Receptor Channels

✍ Scribed by Ramos-Franco, Josefina; Fill, Michael; Mignery, Gregory A.


Book ID
119411432
Publisher
Biophysical Society
Year
1998
Tongue
English
Weight
156 KB
Volume
75
Category
Article
ISSN
0006-3495

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Ca 2Ψ‰ signals mediate the hepatic effects of numerous hormones and growth factors. Hepatic Ca 2Ψ‰ signals are elicited by the inositol trisphosphate receptor, an intracellular Ca 2Ψ‰ channel. Three isoforms of this receptor have been identified; they are expressed and regulated differently. We investi