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Frequent breakpoints in the region surrounding FRA3B in sporadic renal cell carcinomas

✍ Scribed by Shridhar, Viji; Wang, Liang; Rosati, Rita; Paradee, William; Shridhar, Ravi; Mullins, Chadwick; Sakr, Wael; Grignon, David; Miller, Orlando J; Sun, Qi C

Book ID: 110060715
Publisher: Nature Publishing Group
Year: 1997
Tongue: English
Weight: 462 KB
Volume: 14
Category: Article
ISSN: 0950-9232
DOI: 10.1038/sj.onc.1201100

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In a family with a constitutional translocation t(3;6), the oldest member carrying the translocation had developed multiple nonpapillary renal cell carcinomas (RCCs). The translocation breakpoint was positioned between 3p I 3 and 3p 14. I. This is close t o the region in which a t(3;8) breakpoint ha