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Formation of protoporphyrin IX from carboxylic- and amino-derivatives of 5-aminolevulinic acid

✍ Scribed by Miron Kaliszewski; Asta Juzeniene; Petras Juzenas; Miroslaw Kwasny; Jaroslaw Kaminski; Zbigniew Dabrowski; Jerzy Golinski; Johan Moan

Book ID
119625055
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
141 KB
Volume
2
Category
Article
ISSN
1572-1000

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Formation of water-soluble porphyrins an
Formation of water-soluble porphyrins and protoporphyrin IX in 5-aminolevulinic-acid-incubated carcinoma cells
✍ W. Dietel; K. Bolsen; E. Dickson; C. Fritsch; R. Pottier; R. Wendenburg πŸ“‚ Article πŸ“… 1996 πŸ› Elsevier Science 🌐 English βš– 601 KB

The bioconversion of 5-aminolevulinic acid (ALA) into hydrophobic protoporphyrin IX and other water-soluble porphyrins was investigated in Ehrlich ascite carcinoma (EAC) cells and in a myeloma cell line. The effects of irradiation (514 nm), temperature, incubation time and added glucose on the relat

Photobleaching of protoporphyrin IX in c
Photobleaching of protoporphyrin IX in cells incubated with 5-aminolevulinic acid
✍ Johan Moan; Giedre Streckyte; Saulius Bagdonas; Øystein Bech; Kristian Berg πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 French βš– 208 KB πŸ‘ 2 views

Protoporphyrin IX (Pp IX) is the main photosensitizer in photochemotherapy with 5-aminolevulinic acid (ALA). Pp IX is photolabile and the present work shows that 70-95% of Pp IX in cells is degraded by clinically relevant light exposures (40-200 J cm 22 at 630 nm). During light exposure a small yiel