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Formal total synthesis of the trinorguaiane sesquiterpenes (+/−)-clavukerin A and (+/−)-isoclavukerin

✍ Scribed by Jan C Friese; Stefan Krause; Hans J Schäfer

Book ID: 104250825
Publisher: Elsevier Science
Year: 2002
Tongue: French
Weight: 172 KB
Volume: 43
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(02)00402-1

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✦ Synopsis

A formal total synthesis of racemic (+/-)-clavukerin A and (+/-)-isoclavukerin from 4-methylcyclohept-2-en-1-one is presented. The key step involved a Danheiser (trimethylsilyl)cyclopentene annulation.

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