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A Formal Total Synthesis of the Salicylihalamides

✍ Scribed by Christian Herb; Martin E. Maier


Publisher
John Wiley and Sons
Year
2004
Weight
62 KB
Volume
35
Category
Article
ISSN
0931-7597

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## Abstract The paper illustrates two efficient routes to macrolactone **19** containing a 3‐(__para__‐methoxybenzyloxy)propyl side chain at C‐15. The chiral center at C‐15 was introduced by a Noyori reduction of keto ester **5**. The intermediate common to both routes, aldehyde **8**, was prepared