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Total Synthesis of (−)-Salicylihalamide

✍ Scribed by Alois Fürstner; Thorsten Dierkes; Oliver R. Thiel; Gaetano Blanda


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
367 KB
Volume
7
Category
Article
ISSN
0947-6539

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Total Synthesis of Salicylihalamides A a
✍ Christian Herb; Alexander Bayer; Martin E. Maier 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 365 KB 👁 2 views

## Abstract The paper illustrates two efficient routes to macrolactone **19** containing a 3‐(__para__‐methoxybenzyloxy)propyl side chain at C‐15. The chiral center at C‐15 was introduced by a Noyori reduction of keto ester **5**. The intermediate common to both routes, aldehyde **8**, was prepared