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Formal Total Synthesis of Ascidiatrienolide A and the Didemnilactones

✍ Scribed by Alois Fürstner; Monika Schlede


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
226 KB
Volume
344
Category
Article
ISSN
1615-4150

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The Formal Total Synthesis of Epothilone
✍ Markus Kalesse; Monika Quitschalle; Eckhard Claus; Kai Gerlach; Axel Pahl; Hartm 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 347 KB 👁 2 views

The formal total synthesis of epothilone A is described. The 3 is formed by introduction of the thiazole moiety by a Wittig reaction and subsequent functional group transformation. An key steps in the synthesis of the northern hemisphere are a Z-selective ten-membered ring-closing metathesis reactio