𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Folding and assembly of oligomeric proteins in Escherichia coli

✍ Scribed by Carolyn M. Teschke; Jonathan King

Book ID
113404856
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
123 KB
Volume
2
Category
Article
ISSN
0960-9822

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Folding and assembly of oligomeric prote
Folding and assembly of oligomeric proteins in Escherichia coli
✍ Carolyn M. Teschke; Jonathan King πŸ“‚ Article πŸ“… 1992 πŸ› Elsevier Science 🌐 English βš– 640 KB

High levels of expression of oligomeric proteins in heterologous systems are frequently associated with misfolding and accumulation of the polypeptides in inclusion bodies. This reflects aspects of the folding and assembly pathways of oligomeric proteins, which generally proceed from either folding

Expression of correctly folded proteins
Expression of correctly folded proteins in Escherichia coli
✍ George Georgiou; Pascal Valax πŸ“‚ Article πŸ“… 1996 πŸ› Elsevier Science 🌐 English βš– 655 KB

Many heterologous polypeptides fail to fold into their native state when expressed in Escherichia co~i; instead, they are either degraded by the cellular proteolytic machinery or accumulate in insoluble form, typically as inclusion bodies. Misfolding is a particularly vexing problem in the expressio