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Assembly and overexpression of membrane proteins in Escherichia coli

✍ Scribed by David Drew; Linda Fröderberg; Louise Baars; Jan-Willem L de Gier

Book ID
117048182
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
139 KB
Volume
1610
Category
Article
ISSN
0005-2736

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Folding and assembly of oligomeric prote
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✍ Carolyn M. Teschke; Jonathan King 📂 Article 📅 1992 🏛 Elsevier Science 🌐 English ⚖ 640 KB

High levels of expression of oligomeric proteins in heterologous systems are frequently associated with misfolding and accumulation of the polypeptides in inclusion bodies. This reflects aspects of the folding and assembly pathways of oligomeric proteins, which generally proceed from either folding