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Folate-conjugated methoxy poly (ethylene glycol)/poly (L-Alanine) amphiphilic block copolymeric micelles for targeted delivery of paclitaxel

✍ Scribed by Jiao, Zhen; Wang, Xing; Chen, Zhiming

Book ID
120409222
Publisher
Informa plc
Year
2011
Tongue
English
Weight
862 KB
Volume
18
Category
Article
ISSN
1071-7544

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## Abstract Thermosensitive PNVCL‐__b__‐PEG block copolymer coupled with folic acid was prepared as an anti‐cancer drug carrier. This polymer self‐assembled into stable micelles in aqueous solutions at above 33 °C. At 37 °C, the release profile of PNVCL‐__b__‐PEG‐FA micelles showed a slower and mor