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FMOC-polyamide solid phase synthesis of an O-phosphotyrosine-containing tridecapeptide

โœ Scribed by E.A. Kitas; J.W. Perich; J.D. Wade; R.B. Johns; G.W. Tregear


Book ID
104244466
Publisher
Elsevier Science
Year
1989
Tongue
French
Weight
264 KB
Volume
30
Category
Article
ISSN
0040-4039

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โœฆ Synopsis


The incorpmation of O-phosphotyrosine into synthetic peptides using Pmoc-Tyr(PO Me of the modef & )-OH in the Fmoc-polyamide procedure is described uith the preparation yr-tridecapeptide sequence H-Arg-Leu-IZe-GZu-Asp-Asn-GZu-flyr-Thr-Ala-Arg-GZn-GZy-OH.


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โœ Eric A. Kitas; Reinhard Knorr; Arnold Trzeciak; Willi Bannwarth ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› John Wiley and Sons ๐ŸŒ German โš– 883 KB

A number of biologically relevant 04-phospho-~-tyrosine-containing peptides have been synthesized by either the global phosphorylation of the side-chain-unprotected L-tyrosine moiety in presynthesized resin-bound peptides or alternatively by the incorporation of suitably protected 04-phospho-~-tyros