FMOC-polyamide solid phase synthesis of an O-phosphotyrosine-containing tridecapeptide
โ Scribed by E.A. Kitas; J.W. Perich; J.D. Wade; R.B. Johns; G.W. Tregear
- Book ID
- 104244466
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- French
- Weight
- 264 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0040-4039
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โฆ Synopsis
The incorpmation of O-phosphotyrosine into synthetic peptides using Pmoc-Tyr(PO Me of the modef & )-OH in the Fmoc-polyamide procedure is described uith the preparation yr-tridecapeptide sequence H-Arg-Leu-IZe-GZu-Asp-Asn-GZu-flyr-Thr-Ala-Arg-GZn-GZy-OH.
๐ SIMILAR VOLUMES
A number of biologically relevant 04-phospho-~-tyrosine-containing peptides have been synthesized by either the global phosphorylation of the side-chain-unprotected L-tyrosine moiety in presynthesized resin-bound peptides or alternatively by the incorporation of suitably protected 04-phospho-~-tyros