Synthesis of phosphotyrosine-containing peptides by the solid-phase method
โ Scribed by TIAN, ZHENPING ;GU, CHING ;ROESKE, ROGER W. ;ZHOU, MINGMING ;ETTEN, ROBERT L.
- Book ID
- 115099550
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 2009
- Tongue
- English
- Weight
- 383 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0367-8377
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๐ SIMILAR VOLUMES
A series of phosphopeptides Tyr(POsH2)-Val-Pro-Xxx-Leu (Xxx = Met, Met(O), Nle, Dab or Cys), derived from the native platelet-derived growth factor-J3 receptor (PDGF-I3) sequence, has been prepared to study their interaction with the src-homology 2 (SH2) domains of the p85 subunit of PI3 kinase. The
The incorpmation of O-phosphotyrosine into synthetic peptides using Pmoc-Tyr(PO Me of the modef & )-OH in the Fmoc-polyamide procedure is described uith the preparation yr-tridecapeptide sequence H-Arg-Leu-IZe-GZu-Asp-Asn-GZu-flyr-Thr-Ala-Arg-GZn-GZy-OH.