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FLT3-internal tandem duplication in a pediatric patient with t(8;21) acute myeloid leukemia

✍ Scribed by Machiko Kawamura; Hidefumi Kaku; Tateki Ito; Nobuaki Funata; Tomohiko Taki; Akira Shimada; Yasuhide Hayashi

Book ID
118747931
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
491 KB
Volume
203
Category
Article
ISSN
0165-4608

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## Abstract ## BACKGROUND Recently, an internal tandem duplication of the __FLT3__ gene (__FLT3__/ITD) was found in approximately 20% of adult acute myeloid leukemia (AML) cases and associated with a poor outcome. However, there are few studies on __FLT3__/ITD in childhood AML, and the clinical si