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First synthesis of 5-fluoro-(+)-MK7607, its 1-epimer and 6-deoxy derivative

✍ Scribed by João Sardinha; Amelia Pilar Rauter; Matthieu Sollogoub

Publisher: Elsevier Science
Year: 2008
Tongue: French
Weight: 173 KB
Volume: 49
Category: Article
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2008.07.070

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✦ Synopsis

a b s t r a c t (+)-MK7607 is a patented naturally occurring unsaturated pseudo-carbasugar possessing herbicidal activity. We present herein the first synthesis of the 5-fluorinated analogue (1S, 2S, 3R, 4R)-5-fluoro-6-(hydroxymethyl)cyclohex-5-ene-1,2,3,4-tetrol as well as that of two related compounds, namely its 1-epimer and its 6-deoxy derivative.

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