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Synthesis of methyl O-(3-deoxy-3-fluoro-β-d-galactopyranosyl)-(1→6)-O-β-d-galactopyranosyl-(1→6)-3-deoxy-3-fluoro -β-d-galactopyranoside and related n.m.r. studies

✍ Scribed by Pavol Kováč; Cornelis P.J. Glaudemans; Wie Guo; Tuck C. Wong

Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
966 KB
Volume
140
Category
Article
ISSN
0008-6215

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✦ Synopsis

Sequential tritylation, benzoylation, and detritylation of methyl 3-deoxy-3fluoro-AD-galactop~~oside gave crystalline methyl 2,4-di-O-benzoyl-3-deoxy-3-~uoro-ED-gala~opyr~oside (9), which was used as the initial nucleophile in the synthesis of the target otigosaccha~de (16). Treatment of 9 with 2,3,4-&i-0-benzoyl-6-o-bromoacetyl-~-D-g~actop~anosyl bromide gave the corresponding di-R50 R' Rz R3 R4 R5 R6 t H

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