Treatment of benzyl 2-acetamido-2-deoxy-alpha-D-galactopyranoside with 4-methoxybenzaldehyde dimethyl acetal in N,N-dimethylformamide in the presence of 4-toluenesulfonic acid afforded the 4,6-O-(4-methoxybenzylidene) acetal, which was glycosylated with 2,3,4,6-tetra-O-acetyl-alpha-D-galactopyranosy
Synthesis of benzyl O-(3-O-methyl-β-d-galactopyranosyl)-(1 → 3)-2-acetamido-2-deoxy-α-d-galactopyranoside and benzyl O-(β-d-galactopyranosyl)-(1 → 3)-2-acetamido-2-deoxy-6-O-methyl-α-d-galactopyranoside as specific acceptors for sialyltransferases
✍ Scribed by Rakesh K. Jain; Conrad F. Piskorz; E.V. Chandrasekaran; Khushi L. Matta
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 304 KB
- Volume
- 271
- Category
- Article
- ISSN
- 0008-6215
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📜 SIMILAR VOLUMES
In a continuing program for the synthesis of oligosaccharides that occur as part of mutinous glycoconjugates, we previously described\* the synthesis of the disaccharide methyl 3-0-(2-acetamido-2-deoxy-P-D-glucopyranosyl)-a-D-galactopyranoside (1). We have also demonstrated that 1 could be readily
Condensation of benzyl 2-acetamido-4,6-O-benzylidene-2-deoxy-a-D-galactopyranoside with 2,3,4-tri-o-acetyl-a-D-fucopyranosyl bromide in 1: 1 nitromethane-benzene, in the presence of powdered mercuric cyanide, afforded benzyl 2-acetamido-4,6-O-benzylidene-2-deoxy-3-0-(2,3,4-tri-O-acetyl-P-D-fucopyran
Recent years have seen a remarkable surge of interest in the study of U-Lfucosyltransferases. Of these L-fucosyltransferases, the enzyme (143)~a+fucosyltransferase has attracted a great deal of clinical interest as a potential tumor marker. This enzyme catalyzes the transfer of an L-fucosyl group f
Methyl 2,4,6-tri-O-benzyl-P-D-galactopyranoside (5) was obtained crystalline by way of its 3-O-ally] derivative, which was in turn obtained by ring-opening of a presumed 3,4-0-stannylene derivative of methyl p-D-galactopyranoside, followed by benzylation. Condensation of 5 with 2-methyl-(2-acetamido