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First Examples of Transition-Metal Free Sonogashira-Type Couplings

✍ Scribed by Leadbeater, Nicholas E.; Marco, Maria; Tominack, Bonnie J.


Book ID
118276110
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
103 KB
Volume
5
Category
Article
ISSN
1523-7060

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Transition-Metal-Free Sonogashira-Type C
✍ Prasad Appukkuttan; Wim Dehaen; Erik Van der Eycken 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 93 KB 👁 1 views

## Abstract Microwave‐assisted transition‐metal‐free Sonogashira‐type coupling reactions are described. The reactions are run in water as the sole solvent, without the need for copper(I) or any transition‐metal−phosphane complex. The scope of the methodology was tested by reaction of a wide variety