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Transition-Metal-Free Formal Sonogashira Coupling and α-Carbonyl Arylation Reactions

✍ Scribed by Birgit Prüger; Gretchen E. Hofmeister; Christian Borch Jacobsen; David G. Alberg; Martin Nielsen; Karl Anker Jørgensen

Book ID
101839072
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
294 KB
Volume
16
Category
Article
ISSN
0947-6539

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Transition-Metal-Free Sonogashira-Type C
Transition-Metal-Free Sonogashira-Type Coupling Reactions in Water
✍ Prasad Appukkuttan; Wim Dehaen; Erik Van der Eycken 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 93 KB 👁 1 views

## Abstract Microwave‐assisted transition‐metal‐free Sonogashira‐type coupling reactions are described. The reactions are run in water as the sole solvent, without the need for copper(I) or any transition‐metal−phosphane complex. The scope of the methodology was tested by reaction of a wide variety